Prakt. lékáren. 2011; 7(5): 232-235

New medicinal substances in extemporaneous prescription, part 10 - lidocaine and lidocaine hydrochloride

Zbyněk Sklenář1,2,3, Kateřina Horáčková3
1 Farmakologický ústav, 1. LF UK, Praha
2 Vyšší odborná škola zdravotnická, Plzeň
3 Lékárna Na Rohožníku, Praha

The article presents the lidocaine base and its hydrochloride salt as a well-known and long term used local anesthetic agent, shows the

differences in their properties and uses, thus the occurrence of various dosage forms. The article presents the possibilities of preparation

of dosage forms containing lidocaine/lidocaine hydrochloride, because both substances are relatively newly available for magistral

preparations in pharmacies. Examples of formulas suitable for extemporaneous preparations containing lidocaine such as lidocaine

emulgel and polyethylenglycol ointment are also presented.

Keywords: lidocaine emulgel, binary eutectic mixture, lidocaine-polyethyleneglycol ointment, magistral preparation

Published: November 1, 2011  Show citation

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Sklenář Z, Horáčková K. New medicinal substances in extemporaneous prescription, part 10 - lidocaine and lidocaine hydrochloride. Pharmacy for Practice. 2011;7(5):232-235.
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