Prakt. lékáren. 2011; 7(2): 68-70 [Urolog. pro Praxi, 2010; 11(2): 64-67]

Prevention of recurrent urinary tract infections in practice

MUDr.Ladislava Lyerová, CSc.¹, Mgr.Jana Gregorová²

¹ Ambulance nefrologie, Dialyzační středisko BBraun Avitum Bulovka s. r. o., Praha

² Oddělení klinické farmacie, Fakultní nemocnice Na Bulovce, Praha

Recurrent urinary tract infections (UTIs) are a most frequent clinical problem affecting particularly women. Long-term use of antibiotic

prophylaxis, although effective, has its limitations making search for alterative treatments an option. Our recommendation for the prevention

of recurrent UTIs is to use herbal remedies containing cranberry products, D-mannose or nasturtium. Also effective is improvement

of microflora using both oral and vaginal probiotics. However, the most important role in the prevention of these infections is

played by immunotherapy represented primarily by oral vaccines (Uro-Vaxom, Urivac). The efficacy of this product has been confirmed

by a number of studies and meta-analyses. A greater role in clinical practice could be possibly played by vaginal immunization using vaccines

against a variety of pathogens other than E. coli, particularly the vaccine against colonization by Proteus mirabilis currently under

development. In conclusion, immunotherapy can be recommended as a safe, effective and much needed alternative in the prevention

of recurrent urinary tract infections.

Keywords: recurrent urinary tract infections, cranberry products, D-mannose, nasturtium, Uro-Vaxom, Urivac, vaccination

Published: April 5, 2011  Show citation