Prakt. lékáren. 2015; 11(4): 133-136
Cellulose derivatives in extemporaneous preparation
- 1 Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové, Katedra farmaceutické technologie
- 2 Lékárna Scarabeus, Praha
- 3 Lékárna Thomayerovy nemocnice, Praha
Cellulose derivatives, gelatin, and carbomers are the most used excipients for extemporaneous preparation of mucilages and gels. This
article discusses the cellulose derivatives. The pharmacopoeial and best known brand names, the essential physico-chemical properties,
viscosity values of 2 % water dispersions, dispersion techniques are specified, also some examples of the wrong prescriptions still used in
practice are mentioned. Cellulose derivatives should be named according the pharmacopoeia, not using the brand name, and delivered
to the pharmacy with a declared value of viscosity, furthermore other characteristics important for compounding of mucilages and gels.
Regarding the excipients the pharmacist should modify the prescriptions and choose such procedure of compounding to get not only the
effective and stable drug, but also the preparation of the consistency suitable for the prescribed method of dispensing and way of application.
Keywords: mucilage, gel, viscosity, cellulose derivatives, extemporaneous preparation
Published: September 15, 2015 Show citation
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