Prakt. Lékáren. 2018; 14(2e) [Interní Med. 2018; 20(2): 82-84]

Hypolipidemic treatment and target values of lipids

Ondřej Kyselák¹, Vladimír Soška^{1, 2}

¹ Oddělení klinické biochemie, FN u sv. Anny v Brně

² II. interní klinika; Biochemický ústav, Lékařská fakulta MU Brno

Hypolipidemics are one of the most frequently prescribed drugs in the world. Last year, the updated guidelines were released: European Guidelineson cardiovascular disease prevention in clinical practice by European Society of Cardiology (ESC) and ESC/EAS (European AtherosclerosisSociety) Guidelines for the Management of Dyslipidaemias. Both of them contain changes mainly in estimation of individual cardiovascularrisk and target levels of LDL-cholesterol. Targeting these goals is usually very difficult and often impossible in patients with familial hypercholesterolemia.PCSK9 inhibitors are a new and very potent hypolipidemics that should make target LDL-cholesterol levels reachable.

Keywords: dyslipidemia, cardiovascular diseases, LDL cholesterol, triglycerides, statins, PCSK9 inhibitors

Published: June 20, 2018  Show citation