Prakt. Lékáren. 2018; 14(4e) [Klin Farmakol Farm. 2018;32(2):13-19]

Antiparkinsonian drugs, mental disorders in patients with Parkinson’s disease and drug -drug interactions

Michal Prokeš, Josef Suchopár

DrugAgency, a. s., Praha

Patients with Parkinson´s disease (PN), a common neurodegenerative disorder, suffer not only from movement disorder, but also from mentaldisorders including behavioral disorders and psychosis. These disorders are closely related to dopaminergic treatment of PN. Despite knowledgeof the clinical features of these disorders, many patients may not be diagnosed in time. Another issue are drug-drug interactions, because patientswith PN are treated for associated diseases usually by other physicians, who may not always be aware, that the antiparkinsonian or antipsychotic drugs interact with other commonly prescribed drugs. This article introduces the medical public to these problems and shows possible solutions.

Keywords: Parkinson’s disease, antiparkinsonian drugs, antipsychotics, drug interactions, quetiapine

Received: August 30, 2018; Accepted: August 30, 2018; Published: December 15, 2018  Show citation