Prakt. lékáren. 2021; 17(1): e22-e32 [Med. praxi. 2020;17(4):241-246]

Recognizing and treating sarcoidosis

Monika Žurková¹, Vladimíra Lošťáková¹, Petr Jakubec¹, Vítězslav Kolek^†, Eva Kriegová²

¹ Klinika plicních nemocí a TBC, LF UP a FN Olomouc

² Ústav imunologie, LF UP a FN Olomouc

Sarcoidosis is a multisystem granulomatous disease of unknown aetiology that typically affects middle-aged and elderly individuals, most commonly women over 40 years of age. The symptoms that a primary care physician may encounter can be very non-specific. The most characteristic complaints occur in the acute form of the disease, Löfgren syndrome, presenting with a typical bilateral hilar lymphadenopathy detected on chest skiagram, a negative tuberculin test, and an eruption of erythema nodosum in the crural region, often accompanied by bilateral arthritis of the talocrural joint. Löfgren syndrome is usually associated with a good prognosis, with most cases developing spontaneous remission of the disease. When this disease is suspected, an additional chest skiagram is indicated and, in the case of a pathological finding, it is advisable to refer the patient to a pulmonologist.

Keywords: pulmonary sarcoidosis, extrapulmonary involvement, diagnosis, treatment.

Published: April 15, 2021  Show citation