New peroral antidiabetic drugs and heart failure

Jana Jiráčková, Alena Šmahelová

Prakt. Lékáren. 2016; 12(6e)  

Important risk factors of chronic heart failure (CHF) i diabetics represent ischaemic heart disease and arterial hypertension as well as diabetic cardiomyopathy(specific heart tissue impairment of diabetes mellitus). Optimal diabetic compensation is essential for prevention and treatment ofCHF. A wide range of antidiabetic drugs can lower effectively blood glucose as well as improve cardiovascular parameters. Metformin – traditional antidiabetic drug is a very effective insulin sensitizer with positive cardiovascular effect; metformin can be used in patients with compensatedCHF. Gliptins, modern peroral antidiabetic drugs, are used in patients...

Dangerous drugs in patients with renal injury – when and how to reduce the doses

Adéla Hrnčiříková, Jan Vachek

Prakt. Lékáren. 2016; 12(6e)  

Chronic kidney disease (CKD) is defined by reduced glomerular filtration rate, albuminuria, and the cause of renal injury. Kidney disease, particularlyin the elderly population, is frequent; however, due to its asymptomatic nature, it is often overlooked or undiagnosed. If decreased renalfunction is not taken into account when pharmacotherapy is chosen, the patient can easily be harmed. Patients with chronic kidney disease are at an increased risk of adverse effects of pharmacotherapy; in them, kidney disease leads to affecting the majority of pharmacokinetic parametersand, at the same time, the comorbidities typically present require the administration...

Recommended vaccination in adolescent age

Rastislav Maďar

Prakt. Lékáren. 2016; 12(6e)  

Adolescent age is a period when it is possible to continue mandatory, voluntary regular as well as recommended vaccination started in earlierchildhood. In case recommended childhood vaccination has not yet been administered, it can be initiated in a form of a primary vaccinationagainst several diseases. The cathegory stated by legislation as the „vaccination on request“ demands parental agreement with direct payment,with possible partial reimbursement from a health insurance company. Adolescent age should not be overlooked nor underestimated with respectto primary prevention of diseases by means of vaccination. Pediatric primary care physicians...

Phytotherapy in the treatment of benign prostatic hyperplasia – present state i Czech Republic

Luboslav Stárka, Lucie Kolátorová Sosvorová

Prakt. Lékáren. 2016; 12(6e): e23-e30 | DOI: 10.36290/lek.2016.089  

Among the facilities for the treatment of the symptoms of benign prostatic hyperplasia (BPH) herbal preparations are used by millions of menaffected by BPH, though these drugs are not recommended by urological societies due to lack of compliance with the requirements of the medicineof evidence. The results with herbal pharmacy announced in the older literature have a low validity due insufficient standardisation of thepreparations and due to the weak design of the studies. In well-designed studies some positive effects on the low urinary tract syndrome (LUTS) were shown, however, these did not differ dramatically from the effects of placebo. Among...

XXXII. lékárnické dny v Kutné Hoře – obrazová příloha ke zprávě z Prakt. lékáren. 2016; 12(6): 251

Pavel Grodza

Prakt. Lékáren. 2016; 12(6e)  

E-verze 6/16

Prakt. Lékáren. 2016; 12(6e)